Purine nucleotides
Apexbio Technology LLC GTP-Binding Protein Fragment, G alpha 10mg
GTP-Binding Protein Fragment G alpha is a peptide fragment derived from the amino-terminal region of the alpha subunit of GTP-binding proteins It is designed to aid in elucidating the mechanisms of membrane association and -subunit interactions in cell signaling pathways GTP-Binding Protein Fragment G alpha exerts its biological activity by retaining membrane-binding properties independent of the nucleotide-binding state anchoring the protein to the cytoplasmic membrane surface This peptide fragment serves as an experimental tool to study membrane-association mechanisms and signal transduction pathways in biochemical and biomedical research Based on these properties GTP-Binding Protein Fragment G alpha holds research potential in investigating the molecular basis of G protein-mediated signal transduction and protein-membrane interactions
Medchemexpress LLC ATP-Red 1 | 1847485-97-5 | 561.48 | 112.29 UG
ATP-Red 1 is a multisite-binding switchable fluorescent probe that selectively and rapidly responds to intracellular concentrations of ATP in living cells (Ex/Em = 510/590 nm). It is for research use only.
- Multisite-binding switchable fluorescent probe
- Selectively and rapidly responds to intracellular ATP in living cells
- Excitation/Emission (Ex/Em) = 510/590 nm
- Appearance: Solid
- Color: Pale purple to purple
![Alkali Scientific Adenosine, Free Base [9 β D Ribofuranosyladenine], 1 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660179.jpg-250.jpg)
Alkali Scientific Adenosine, Free Base [9 β D Ribofuranosyladenine], 1 Kg
Adenosine, Free Base [9 β D Ribofuranosyladenine], is a biochemical reagent used primarily for research in cellular and molecular biology. This 1 kg quantity is ideal for large-scale experiments involving nucleoside analogs. As a purine nucleoside, it is essential for a variety of biochemical assays and metabolic research, particularly in energy metabolism and nucleotide signaling. Adenosine plays a crucial role in cellular energy transfer, DNA synthesis, and cell signaling. This product is widely used in biochemical research related to metabolic pathways, enzyme kinetics, and nucleotide interactions in human and animal models.
![Alkali Scientific ATP [Adenosine 5' triphosphate, disodium salt trihydrate], 100 Grams](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660658.jpg-250.jpg)
Alkali Scientific ATP [Adenosine 5' triphosphate, disodium salt trihydrate], 100 Grams
Adenosine 5' Triphosphate (ATP), disodium salt trihydrate, is a key energy molecule used in numerous biochemical applications, including enzyme assays, protein synthesis, and cellular energy metabolism studies. As a high-energy phosphate compound, ATP is essential for driving a wide variety of cellular processes, such as active transport, muscle contraction, and biosynthesis. In laboratories, ATP is commonly used to measure cellular energy levels, study enzyme kinetics, and assess cellular responses to various stimuli. This 100g bottle is perfect for large-scale experiments requiring ATP as a substrate or energy source for in vitro assays and biochemical research.
Medchemexpress LLC NHC-triphosphate tetraammonium | 97.09% | 567.28 | 1 MG
NHC-triphosphate tetraammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) in its triphosphate form. It acts as a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.
- May directly target the viral polymerase and act as a nonobligate chain terminator
- Plays a significant role in inhibiting early negative-strand RNA synthesis
- Interferes with correct replicase complex formation through chain termination or mutagenesis
Medchemexpress LLC Adenosine 5'-triphosphate-13C10,15N5 dilithium | 56-65-5 | 13C10H14Li215N5O13P3 | 1 MG
Adenosine 5'-triphosphate-13C10,15N5 dilithium is a 13C and 15N labeled dilithium salt form of Adenosine 5'-triphosphate. It is a central component of energy storage and metabolism in vivo, providing metabolic energy for pumps and serving as a coenzyme in cells. It also functions as an important endogenous signaling molecule in immunity and inflammation.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Provides metabolic energy to drive metabolic pumps
- Serves as a coenzyme in cells
- Acts as an endogenous signaling molecule in immunity and inflammation
![Alkali Scientific AMP [Adenosine 5 Monophosphate, Free Acid], 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660300.jpg-250.jpg)
Alkali Scientific AMP [Adenosine 5 Monophosphate, Free Acid], 1 G
Adenosine 5' Monophosphate (AMP), Free Acid, is a nucleotide reagent commonly used in laboratory applications such as enzyme assays, molecular biology, and biochemistry. AMP serves as an essential building block for RNA synthesis and plays a key role in energy transfer within cells as part of the ATP/ADP cycle. This 1g sample is suitable for use in various assays, including kinase activity assays, cell signaling studies, and the synthesis of RNA oligonucleotides. AMP is also involved in ATP-dependent processes and is widely used in research on cellular metabolism, signal transduction, and DNA/RNA synthesis in biochemical studies.
Medchemexpress LLC Adenosine monophosphate-15N5 dilithium | 61-19-8 | 99.22% | C10H12Li215N5O7P | 5 MG
Adenosine monophosphate-15N5 dilithium is the 15N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist and has significant antiviral activity against HSV-1 and HSV-2. It is a key cellular metabolite regulating energy homeostasis and signal transduction. This compound can be used as a tracer and an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules as tracers
- Potential to affect the pharmacokinetic and metabolic profiles of drugs
- Product of various enzymatic reactions, many of which are dysregulated during disease conditions
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: Solution, -20°C, 2 years
![Alkali Scientific Adenosine, Free Base [9 β D Ribofuranosyladenine], 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661074.jpg-250.jpg)
Alkali Scientific Adenosine, Free Base [9 β D Ribofuranosyladenine], 5 G
Adenosine, Free Base [9 β D Ribofuranosyladenine], 5 G is a specialized reagent used in biochemical and molecular biology research. This nucleoside is essential for the study of cellular energy metabolism and signal transduction pathways. Adenosine plays a vital role in the production of ATP, RNA, and DNA. It is widely used in assays that explore nucleotide metabolism, enzyme kinetics, and cell signaling mechanisms. As a fundamental building block for cellular functions, it is used in research on diseases like cancer, heart disease, and neurodegenerative conditions, where nucleotide metabolism is altered or dysregulated.
Medchemexpress LLC Adenosine dialdehyde | 34240-05-6 | MFCD00056960 | >98.0% | 265.23 g/mol | C10H11N5O4 | 5MG
Adenosine dialdehyde is a purine nucleoside analogue that potently inhibits S-adenosylhomocysteine hydrolase (SAHH). It is used as a research reagent in biochemical and cellular studies to probe methylation pathways and methyltransferase activity. The compound is a crystalline solid with molecular weight 265.23 g/mol and formula C10H11N5O4, and it is soluble in DMSO.
Apexbio Technology LLC 8-Azido-ATP(Synonyms: 8-Azidoadenosine 5'-triphosphate, 8-N3-ATP, 8-Azido-ATP, 8-Azidoadenosine triphosphate), 10ul (100 mM).
8-Azido-ATP is a ribonucleoside triphosphate analog with an azido group substitution at the adenine C-8 position It acts primarily as an ATP mimic interacting with poly(A) polymerase (PAP) specifically illustrated using yeast poly(A) polymerase (yPAP) Incorporation of 8-azido-ATP into growing polyadenylation chains results in premature termination and moderately shorter poly(A) tails relative to natural ATP substrates Due to its chain-terminating capacity and altered substrate specificity 8-azido-ATP is applied in biochemical studies examining enzyme fidelity nucleotide selection mechanisms and RNA polymerase activity
Medchemexpress LLC 7-Methyl-guanosine-5'-triphosphate sodium | 25 MG
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. Its phosphorothioate analog acts as a potent cap-dependent translation inhibitor.
- Is a guanosine 5'-phosphate.
- Functions as a potent cap-dependent translation inhibitor.
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 100ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5′-triphosphate sodium salt hydrate, 36051-31-7, MFCD00077781, 250 mg
Empirical Formula (Hill Notation): C10H16N5O14P3 · xNa+, Molecular Weight: 523.18 (free acid basis), ≥95% (HPLC), powder, Synonym: GTP. Guanosine 5′-triphosphate sodium salt hydrate has been used: in the preparation of horseradish peroxidase (HRP)-modified platination reagents, in whole cell, voltage-clamp recordings, and in in vitro inhibition of transglutaminase (tTG).
Apexbio Technology LLC Adenosine 5'-monophosphate disodium 4578-31-8 1g
Adenosine 5p-monophosphate disodium is a purine nucleotide derivative composed of adenosine linked to a phosphate group presented as the disodium salt It functions as an intermediate in cellular metabolism contributing directly to ATP biosynthesis and degradation pathways and serves as a biochemical precursor and degradation product in energy exchange reactions Adenosine 5p-monophosphate disodium exerts its biological activity as part of pathways regulating gene expression protein synthesis modulation and intracellular signal transduction In biomedical research it is utilized to investigate mechanisms underlying energy metabolism nucleic acid metabolism and cellular homeostasis Based on these characteristics Adenosine 5p-monophosphate disodium holds research potential in studies of metabolic function ATP-dependent signaling pathways and related disease models